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Found 32 results
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Kerkvliet, Nancy I
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2018
A. K. Ehrlich
,
Pennington, J. M.
,
Bisson, W. H.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiation.
”
,
Toxicol Sci
, 2018.
2017
A. K. Ehrlich
,
Pennington, J. M.
,
Tilton, S.
,
Wang, X.
,
Marshall, N. B.
,
Rohlman, D.
,
Funatake, C.
,
Punj, S.
,
O'Donnell, E. F.
,
Yu, Z.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells.
”
,
Eur J Immunol
, vol. 47, no. 11, pp. 1989-2001, 2017.
E. F. O'Donnell
,
Jang, H. Sang
,
Pearce, M. C.
,
Kerkvliet, N. I.
, and
Kolluri, S.
,
“
The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells.
”
,
Oncotarget
, vol. 8, no. 15, pp. 25211-25225, 2017.
H. Jang
,
Pearce, M. C.
,
O'Donnell, E. F.
,
Nguyen, B.
,
Truong, L.
,
Mueller, M. J.
,
Bisson, W. H.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
, and
Kolluri, S.
,
“
Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells
”
,
Biology (Basel)
, vol. 6, no. 4, 2017.
H. Sang Jang
,
Pearce, M. C.
,
O'Donnell, E. F.
,
Nguyen, B. Duc
,
Truong, L.
,
Mueller, M. J.
,
Bisson, W. H.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
, and
Kolluri, S.
,
“
Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.
”
,
Biology (Basel)
, vol. 6, no. 4, 2017.
2016
A. K. Ehrlich
,
Pennington, J. M.
,
Wang, X.
,
Rohlman, D.
,
Punj, S.
,
Löhr, C. V.
,
Newman, M. T.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.
”
,
J Immunol
, vol. 196, no. 1, pp. 264-73, 2016.
2015
D. C. Koch
,
Jang, H. S.
,
O'Donnell, E. F.
,
Punj, S.
,
Kopparapu, P. R.
,
Bisson, W. H.
,
Kerkvliet, N. I.
, and
Kolluri, S.
,
“
Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1.
”
,
Oncogene
, 2015.
2014
S. Punj
,
Kopparapu, P.
,
Jang, H. Sang
,
Phillips, J. Lynne
,
Pennington, J. M.
,
Rohlman, D.
,
O'Donnell, E. F.
,
Iversen, P. L.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.
”
,
PLoS One
, vol. 9, no. 2, p. e88726, 2014.
A. Perkins
,
Phillips, J. Lynne
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Perdew, G. H.
,
Kolluri, S. K.
, and
Bisson, W. H.
,
“
A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain.
”
,
Biology (Basel)
, vol. 3, no. 4, pp. 645-69, 2014.
A. Perkins
,
Phillips, J. Lynne
,
Kerkvliet, N. I.
,
Tanguay, R.
,
Perdew, G. H.
,
Kolluri, S.
, and
Bisson, W. H.
,
“
A structural switch between agonist and antagonist bound conformations for a ligand-optimized model of the human aryl hydrocarbon receptor ligand binding domain
”
,
Biology
, vol. 3, pp. 645–669, 2014.
2012
E. F. O'Donnell
,
Kopparapu, P. Rao
,
Koch, D. C.
,
Jang, H. Sang
,
Phillips, J. Lynne
,
Tanguay, R. L.
,
Kerkvliet, N. I.
, and
Kolluri, S. Kumar
,
“
The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.
”
,
PLoS One
, vol. 7, no. 7, p. e40926, 2012.
2010
E. F. O'Donnell
,
Saili, K. S.
,
Koch, D. C.
,
Kopparapu, P. R.
,
Farrer, D.
,
Bisson, W. H.
,
Mathew, L. K.
,
Sengupta, S.
,
Kerkvliet, N. I.
,
Tanguay, R.
, and
,
“
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor
”
,
PLoS One
, vol. 5, p. e13128, 2010.
E. F. O'Donnell
,
Saili, K. S.
,
Koch, D. C.
,
Kopparapu, P. R.
,
Farrer, D.
,
Bisson, W. H.
,
Mathew, L. K.
,
Sengupta, S.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
, and
Kolluri, S. Kumar
,
“
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.
”
,
PLoS One
, vol. 5, no. 10, 2010.
2009
W. H. Bisson
,
Koch, D. C.
,
O'Donnell, E. F.
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S. Kumar
,
“
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.
”
,
J Med Chem
, vol. 52, no. 18, pp. 5635-41, 2009.
W. H. Bisson
,
Koch, D. C.
,
O'Donnell, E. F.
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S. Kumar
,
“
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands
”
,
Journal of medicinal chemistry
, vol. 52, pp. 5635–5641, 2009.
W. H. Bisson
,
Koch, D. C.
,
Donnell, E. F. ’
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S.
,
“
Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands
”
,
Journal of Medicinal Chemistry
, vol. 52, no. 18, pp. 5635 - 5641, 2009.
2008
C. J. Funatake
,
Marshall, N. B.
, and
Kerkvliet, N. I.
,
“
Advertisement In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon Receptor
”
,
Journal of Immunotoxicology
, vol. 5, no. 1, pp. 81 - 91, 2008.
2005
C. J. Funatake
,
Marshall, N. B.
,
Steppan, L. B.
,
Mourich, D. V.
, and
Kerkvliet, N. I.
,
“
Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells.
”
,
J Immunol
, vol. 175, no. 7, pp. 4184-8, 2005.
B. Mahadevan
,
Luch, A.
,
Bravo, C. F.
,
Atkin, J.
,
Steppan, L. B.
,
Pereira, C. B.
,
Kerkvliet, N. I.
, and
Baird, W. M.
,
“
Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo.
”
,
Cancer Lett
, vol. 227, no. 1, pp. 25-32, 2005.
B. Mahadevan
,
Luch, A.
,
Bravo, C. F.
,
Atkin, J.
,
Steppan, L. B.
,
Pereira, C. B.
,
Kerkvliet, N. I.
, and
Baird, W. M.
,
“
Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo
”
,
Cancer Letters
, vol. 227, no. 1, pp. 25 - 32, 2005.
2004
C. J. Funatake
and
Kerkvliet, N. I.
,
“
Early Consequences of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure on the Activation and Survival of Antigen-Specific T Cells
”
,
Toxicological Sciences
, vol. 82, no. 1, pp. 129 - 142, 2004.
2003
J. - Y. Choi
,
Oughton, J. A.
, and
Kerkvliet, N. I.
,
“
Functional alterations in CD11b(+)Gr-1(+) cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
”
,
Int Immunopharmacol
, vol. 3, no. 4, pp. 553-70, 2003.
B. A. Vorderstrasse
and
Kerkvliet, N. I.
,
“
Influence of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on the Antigen-Presenting Activity of Dendritic Cells
”
,
Toxicological Sciences
, vol. 72, no. 1, pp. 103 - 112, 2003.
2002
C. E. Ruby
,
Leid, M.
, and
Kerkvliet, N. I.
,
“
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis Factor-$\alpha$ and Anti-CD40–Induced Activation of NF-$ąppa$B/Rel in dendritic cells: p50 Homodimer Activation is not affected
”
,
Molecular pharmacology
, vol. 62, pp. 722–728, 2002.
J. R. Maxwell
,
Ruby, C.
,
Kerkvliet, N. I.
, and
Vella, A. T.
,
“
Contrasting the roles of costimulation and the natural adjuvant lipopolysaccharide during the induction of T cell immunity
”
,
The Journal of Immunology
, vol. 168, pp. 4372–4381, 2002.
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